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Retatrutide at 12 mg produced 24.2% body weight loss in phase 2 trials, the highest of any single-agent compound tested
If monthly dosing becomes real, it may come from a combination of molecular design and dosing choreographyweekly titration up, then monthly maintenance downshiftrather than a single magic half-life number
While AOD-9604 has shown minimal interactions in studies, individual situations vary, particularly when multiple medications are involved
Authors interpretation The study authors suggest these results are an early yet optimistic indicator that GLP1RAs might represent a new pharmacologic approach for BED and BN through both metabolic and neurobiological mechanisms
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